AICAR 50 mg
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AICAR 50 mg

AMPK-Activating Metabolic Research Peptide

  • Substance: AICAR (Acadesine)
  • Strength: 50 mg/vial
  • Form: Lyophilized powder
  • Packaging: 2 mL glass vial
  • Manufacturer: Dragon Pharma, Europe
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Dragon Pharma AICAR

AICAR 50 mg delivers a potent dose of Acadesine, a groundbreaking research peptide known for its unique ability to activate AMP-activated protein kinase (AMPK). This enzyme serves as the master cellular "energy sensor," playing a pivotal role in regulating metabolism, glucose uptake, and mitochondrial biogenesis. Originally researched for cardiac ischemia, AICAR's potential to mimic the metabolic effects of exercise—even without physical activity—has made it a significant subject of study in sports science and body composition research.

For bodybuilders and endurance athletes in the USA, the research around Dragon Pharma AICAR 50 mg focuses on its dual-action potential: enhancing fat oxidation and improving muscular endurance. By activating AMPK, it may promote a metabolic shift towards using fat as a primary fuel source while increasing glucose uptake into muscle cells, effectively "reprogramming" energy metabolism. This makes it particularly interesting for cutting phases, endurance training research, and protocols aimed at improving cardiovascular efficiency. Manufactured by Dragon Pharma in certified European facilities, this 50 mg lyophilized powder vial offers high concentration and purity for precise research applications, backed by rigorous quality assurance standards.

Key Benefits:

  • Exercise Mimetic Effect: Activates AMPK to simulate cellular responses similar to endurance training, enhancing metabolic conditioning.
  • Enhanced Fat Oxidation: Promotes metabolic shift toward fat as primary energy source, supporting lean physique goals.
  • Increased Endurance Capacity: Research suggests improved glucose uptake and mitochondrial efficiency may delay fatigue onset.
  • Metabolic Flexibility: Helps optimize the body's ability to switch between fuel sources (carbs and fats) efficiently.
  • High Concentration Formula: 50 mg per vial provides ample material for extended research protocols and precise dosing studies.

Each 2 mL vial contains 50 mg of highly pure AICAR (Acadesine) as a lyophilized powder, manufactured under strict pharmaceutical-grade quality control standards in Dragon Pharma's certified research facilities.

Product Specifications

Product Name AICAR 50 mg
Manufacturer Dragon Pharma
Substance AICAR (Acadesine)
Packaging 2 mL glass vial, lyophilized powder
Lab Test Result ≥ 98% Purity (HPLC verified)
Half-Life Approximately 6-8 hours (research data)
Recommended Cycle Research protocols typically range from 4-8 weeks, often with daily or EOD administration.
Form Lyophilized (freeze-dried) powder for reconstitution
Aromatization Not applicable (non-hormonal metabolic compound)
Dosage (Research Models) Varies significantly in preclinical studies; not for human consumption.

Usage Guidelines

Research Disclaimer: The following is synthesized from scientific literature for educational purposes. Dragon Pharma AICAR 50 mg is a research chemical for laboratory study only, not for human consumption.

In experimental settings, AICAR is typically reconstituted with bacteriostatic water. Research models often explore subcutaneous administration. The half-life supports once or twice-daily dosing in many protocols. Due to its AMPK-activating mechanism, researchers often study it alongside exercise models or with other compounds that affect metabolism and insulin sensitivity for synergistic effects.

  • Experimental Metabolic Study (4-6 weeks): Common in research aiming to observe shifts in fuel utilization and endurance markers, often combined with controlled diet protocols.
  • Long-term Adaptation Research (8+ weeks): Used in studies examining mitochondrial biogenesis and long-term metabolic reprogramming effects.

Post Cycle Therapy (PCT):

AICAR does not affect the HPTA, so traditional PCT with SERMs like Enclomiphene or Raloxifene is unnecessary. However, research into maintaining metabolic adaptations post-cycle is relevant. Compounds like MK-677 (Ibutamoren) may be studied for their potential to support growth hormone secretion and metabolic rate. Monitoring insulin sensitivity markers post-research is recommended.

Support & Synergy in Research:

For comprehensive metabolic research, AICAR is often studied alongside other compounds. GW501516 (Cardarine) is a common research pairing for examining combined AMPK and PPAR-delta activation on endurance and fat loss. To support overall wellness in experimental models, SS-31 (for mitochondrial protection) or L-Carnitine (for fatty acid transport) may be incorporated into study designs.

Storage Instructions

Proper storage is essential to maintain the stability of this research peptide.

  • Unreconstituted Powder: Store the sealed vial in a freezer at or below -20°C (-4°F). In this state, AICAR remains stable for up to 24 months. Protect from light and avoid temperature fluctuations.
  • After Reconstitution: Once mixed with bacteriostatic water, the solution should be stored immediately in a refrigerator at 2°C to 8°C (36°F to 46°F). The reconstituted solution is typically stable for 20-30 days when refrigerated. Do not freeze the liquid solution.
  • Handling: Use aseptic technique during reconstitution to prevent contamination. Keep vials in their original packaging until use.

What is AICAR used for?

AICAR is a research compound primarily studied for its ability to activate AMP-activated protein kinase (AMPK). This activation mimics some cellular effects of exercise, leading to research into enhanced endurance, improved fat burning, increased glucose uptake by muscles, and mitochondrial biogenesis. It's a key subject in metabolic and sports performance research.

What are the long-term effects of AICAR?

Long-term research data is limited. Theoretical long-term effects based on its mechanism could include sustained improvements in metabolic flexibility and mitochondrial density. However, as with any potent metabolic modulator, prolonged use in research models requires careful monitoring of glucose homeostasis, liver enzymes, and potential adaptation (downregulation) of the AMPK pathway itself.

How does AICAR differ from GW501516 (Cardarine)?

While both are researched for endurance and fat loss, they work through different pathways. AICAR activates AMPK (the "energy sensor"), mimicking exercise. GW501516 activates PPAR-delta, influencing genes related to fat burning and endurance. They are often studied in combination for potential synergistic effects on metabolic performance.

Is Dragon Pharma AICAR 50 mg pure?

Yes. Dragon Pharma subjects every batch to independent third-party HPLC and Mass Spec testing, verifying a minimum purity of 98%. The Certificate of Analysis confirms the identity, purity, and absence of harmful contaminants, ensuring it meets high standards for research purposes.

What is the best way to reconstitute AICAR?

For research use, reconstitute the 50 mg lyophilized powder with an appropriate volume of sterile bacteriostatic water to achieve the desired concentration. Gently swirl the vial until the powder is fully dissolved—avoid vigorous shaking to prevent peptide degradation. Use sterile syringes and practice aseptic technique throughout.

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