Long-Acting Growth Hormone-Releasing Hormone Analog
CJC-1295 DAC 5 mg delivers a potent, long-acting analog of Growth Hormone-Releasing Hormone (GHRH), engineered with a revolutionary Drug Affinity Complex (DAC) that fundamentally alters its pharmacokinetic profile. The DAC moiety enables covalent binding to serum albumin upon administration, creating a circulating reservoir that slowly releases the active peptide over an extended period. This results in an exceptionally long half-life of approximately 7-10 days, compared to minutes for the native GHRH hormone or the "No DAC" version. The sustained presence of CJC-1295 DAC provides continuous stimulation of the pituitary gland to release growth hormone (GH), leading to stable, elevated IGF-1 levels for prolonged periods from a single administration.
For bodybuilders, athletes, and anti-aging researchers in the USA, Dragon Pharma CJC-1295 DAC 5 mg offers a unique research paradigm focused on sustained anabolic and metabolic stimulation. Unlike pulsatile GH secretagogues, CJC-1295 DAC creates a more constant "background" elevation of GH and IGF-1, which may be particularly useful in studies examining long-term tissue repair, chronic injury healing, and sustained improvements in body composition. This makes it a compelling research tool for protocols that benefit from continuous exposure rather than intermittent pulses. Manufactured by Dragon Pharma in certified European laboratories, each 5 mg vial of lyophilized powder represents the pinnacle of peptide engineering, providing researchers with a consistent, high-purity compound for investigating prolonged endocrine modulation.
Key Benefits:
Each 2 mL vial contains 5 mg of high-purity CJC-1295 with Drug Affinity Complex as a sterile lyophilized powder, synthesized using advanced peptide chemistry under Dragon Pharma's rigorous quality control standards.
| Product Name | CJC-1295 DAC 5 mg |
| Manufacturer | Dragon Pharma |
| Substance | CJC-1295 with Drug Affinity Complex (DAC) |
| Packaging | 2 mL glass vial, lyophilized powder |
| Lab Test Result | ≥ 98% Purity (HPLC verified, correct DAC conjugation) |
| Half-Life | Approximately 7-10 days (extended due to albumin binding) |
| Recommended Cycle | Research cycles typically range from 8-12 weeks, given its long-acting nature and cumulative effects. |
| Form | Lyophilized (freeze-dried) powder for reconstitution |
| Aromatization | Not applicable (non-hormonal peptide) |
| Dosage (Research Models) | Typically studied with once or twice-weekly subcutaneous administration due to extended half-life. |
Research Application Only: This information is derived from scientific literature for educational purposes. Dragon Pharma CJC-1295 DAC 5 mg is a research chemical for laboratory investigation only, not for human consumption.
In experimental settings, CJC-1295 DAC is reconstituted with bacteriostatic water. Its extraordinary half-life allows for very infrequent dosing—once or twice weekly is standard in research protocols. Studies often begin with a single weekly dose to establish baseline effects. Due to its continuous action, research monitoring should include regular assessment of IGF-1 levels, glucose metabolism, and potential fluid retention. Subcutaneous administration is most common in preclinical models. The sustained nature of its effects means research outcomes are typically evaluated over weeks rather than days.
As a GHRH analog, CJC-1295 DAC does not suppress the hypothalamic-pituitary-gonadal (HPG) axis, so traditional PCT with SERMs like Nolvadex is not indicated. However, due to its long-acting nature and potential for pituitary desensitization with prolonged use, research protocols typically include a washout period of 4-6 weeks after a cycle. Some studies incorporate a switch to a pulsatile secretagogue like Ipamorelin or the CJC No DAC/Ipamorelin blend during the off-period to maintain some GH stimulation while allowing receptor recovery.
CJC-1295 DAC is often studied in combination with other compounds. For enhanced anabolic research, it can be paired with SARMs like YK-11 (a myostatin inhibitor) or MK-2866 (Ostarine). For fat loss synergy, researchers may combine it with GW501516 (Cardarine). Due to potential effects on blood sugar, monitoring glucose and considering support with compounds like Sermorelin (which may have different metabolic effects) could be part of comprehensive study designs.
Proper storage is essential to maintain the stability of this advanced peptide conjugate.
The choice depends on research goals. CJC-1295 WITH DAC provides sustained, long-lasting GH elevation from infrequent dosing (1-2x weekly), ideal for studies of continuous anabolic/metabolic effects. CJC-1295 WITHOUT DAC produces brief, pulsatile GH releases (requiring daily dosing) that mimic natural secretion, better for research on physiological rhythms. "With DAC" offers convenience and sustained action; "Without DAC" offers more natural pulsatility.
DAC stands for "Drug Affinity Complex." It is a chemical moiety (Lys-Lys-Gly) attached to the CJC-1295 peptide that enables it to bind covalently to serum albumin in the bloodstream upon administration. This binding creates a circulating reservoir that slowly releases the active peptide over time, extending its half-life from minutes to approximately 7-10 days. This is the key technological innovation behind CJC-1295 DAC.
In research, CJC-1295 (both with and without DAC) acts as a potent analog of Growth Hormone-Releasing Hormone (GHRH). It stimulates the pituitary gland to release growth hormone (GH), which then stimulates the liver to produce Insulin-like Growth Factor 1 (IGF-1). This activates the GH/IGF-1 axis, leading to research outcomes focused on increased protein synthesis, enhanced fat metabolism, improved recovery and healing, and potential anti-aging effects.
Research does not primarily focus on CJC-1295 as a direct testosterone booster. Its main action is on the GH/IGF-1 axis. However, optimizing GH levels may create a more anabolic environment and improve overall endocrine function. For research specifically targeting testosterone, compounds like Enclomiphene (a SERM) or Proviron (Mesterolone) would be more relevant subjects of study.
Due to its extended half-life of 7-10 days, CJC-1295 DAC is typically administered once or twice weekly in research protocols. This infrequent dosing is a major advantage for long-term studies, as it maintains stable, elevated IGF-1 levels with minimal administrations. Some protocols use a loading dose followed by weekly maintenance doses to quickly establish steady-state concentrations.